Hyperimmune Thrombocytopenia in Pregnancy Treated by Splenectomy

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Hyperimmune thrombocytopenia in pregnancy treated by splenectomy.

3 cases of hyperimmune thrombocytopenia in pregnancy are described. Splenectomy was followed by return of the platelet count to normal in all. There was no maternal or fetal death. Liam G. O’Connell, MD, MSc, Consultant Haematologist, St. Vincent’s Hospital, Elm Park, Dublin 4 (Ireland) Hyperimmune thrombocytopenia (HTP) in pregnancy represents a hazard to both mother andfetus. Prednisone i...

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Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy

Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphos...

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Splenectomy for immune thrombocytopenia.

As with most reports of splenectomy for immune thrombocytopenia, the recent study claiming efficacy of splenectomy for human immunodeficiency virus (HIV)-related thrombocytopenia is uncontrolled, and combines responses of more and less severely thrombocytopenic patients.' In addition, important information is omitted. What were the mean platelet count increases, partial versus complete response...

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Thrombocytopenia in pregnancy.

Thrombocytopenia occurs commonly during pregnancy, and may result from diverse etiologies. Awareness of these many causes facilitates proper diagnosis and management of thrombocytopenia in the pregnant setting. Some causes of thrombocytopenia are unique to pregnancy and may not be familiar to hematologists. In the review, we will discuss the differential diagnosis of thrombocytopenia in pregnan...

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Thrombocytopenia in pregnancy.

Thrombocytopenia is defined as a platelet count of less than 150 x 109/l. Normal pregnancy is generally thought not to affect the platelet count,' but it has been suggested that the normal range is lower in pregnancy, and that the count falls in the third trimester.2`4 This review concentrates on causes of thrombocytopenia with particular reference to pregnancy: most of these involve excessive ...

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ژورنال

عنوان ژورنال: Acta Haematologica

سال: 1978

ISSN: 0001-5792,1421-9662

DOI: 10.1159/000207778